ENLIGHTENMENT TO ERFECTION
Department of Bio-Technology

Dr. Ranadhir Chakraborty


M.Sc., Ph.D.

Professor

Members of Learned Societies: Life Member, Society of Biological Chemists (INDIA)


Contact Addresses:

Phone +91- 9434872273(M)
Mailing Address Department of Bio-Technolgy, University of North Bengal, Raja Rammohanpur, P.O.- NBU, Dist- Darjeeling, West Bengal, Pin -734013, India.
e-Mail rcnbusiliguri@gmail.com

Subject specialization: Molecular Microbiology

Areas of Research Interest: Microbial genetics, Microbial genomics

No. of Ph.D. students:    (a) Supervised: 09 (Awarded); 02 (Submitted)      (b) Ongoing: 06 (Registered).

No. of M.Phil. students: (a) Supervised: Nil       (b) Ongoing: Nil .

No. of Publications:        (a) Journal(s) : 49    (b) No. of Books : 10     (c) No. of Books Edited: 01      (d) International Journal Volume Edited: 01

Achievement & Awards:

Professional Experience:

S. No.

Course/Paper

Level

Mode of teaching*

Hours per week allotted

1.

Semester-I; Molecular Biology

PG

L

02

2.

Semester-I; Lab II- Molecular Biology

PG

P

03

3.

Semester-II; Microbiology and Industrial Applications

PG

L

01

4.

Semester-II; Genetics

PG

L

01

5.

Semester-II; Genetic Engineering

PG

L

01

6.

Semester-II; Lab-IV-Microbiology

PG

P

03

7.

Semester-II; Lab-V- Genetic Engineering

PG

P

01

8.

Semester-III, Bioprocess Engineering & Technology

PG

L

02

9.

Semester-III, IPR & Biosafety

PG

L

01

10.

Semester-III, Lab VI- Bioprocess Engineering & Technology

PG

P

02

11.

Semester-III; Lab-VII- Based on Elective

PG

P

01

12

Semester-IV; Bioentrepreneurship

PG

L

03

13.

Semester-IV; Project Work

PG

L,P,S, T,

15

*Lecture (L), Seminar(S), Tutorial (T), Practical (P), Contact Hours (C)

 

 

 

 

 

 

 

 

 

S. No.

Type of Activity

Average Hrs/Week

 

Extension, Co-curricular & field based Activities

 

1.

Floriculture and Horticulture technical consultancy, training

06

Contribution to Corporate Life and Management of the Institution

Yearly/Semester wise responsibilities

2.

Head of the Department since September 2004

All responsibilities in running the department

3.

Member of the Honorable Court, NBU, since 2004

4.

Course Corrdinator of the DBT sponsored M.Sc course in Biotechnology

To act as the bridge between DBT, GoI, & NBU

Professional Development Activities

5.

Delivering lectures in every Orientation Courses since inception of the Academic Staff College, NBU

6.

Participating as experts in Government organized Skill-development programmes including workshops


Administrative Experiences:

Selective List of Publications:

            Edited Books:
  1. Amit Basak (Editor), Ranadhir Chakraborty (Editor), Santi M. Mandal (Editor). 2016.  Recent Trends in Antifungal Agents and Antifungal Therapy. Publisher: Springer; 1st ed. 2016 edition (5 June 2016)  ISBN-10: 8132227808 ISBN-13: 978-8132227809.

    Book Chapters:

  2. Bhowal S, Chakraborty R. 2015.MICROBIAL DIVERSITY OF ACIDOPHILIC HETEROTROPHIC BACTERIA: AN OVERVIEW. In Biodiversity, Conservation and Sustainable Development Vol.I Issues and Approaches, Edition: Volume I, Chapter: 17, Publisher: New Academic Publishers, New Delhi 2015, Editors: Prithwiraj Jha, pp.157-
  3. Cray JA, Bhaganna P, Singhal RS, Patil SV, Saha D, Chakraborty R, Iwaguchi S, Timson DJ, Hallsworth JE. 2014. Chaotropic and Hydrophobic Stress Mechanisms of Antifungal Substances. In: Dehne HW; Deising HB; Fraaije B; Gisi U; Hermann D; Mehl A; Oerke EC; Russell PE; Stammler G; Kuck KH; Lyr H (Eds), "Modern Fungicides and Antifungal Compounds", Vol.VII, pp. 73-80. © 2014 Deutsche Phytomedizinische Gesellschaft, Braunschweig, ISBN: 978-3-941261-13-6.
  4. Chakraborty R, Kumar A, Mukherjee S, Saha Bhowal S, Mandal AK, Tiwary BK. 2013. Oligotrophic bacteria of River Mahananda: Spanking reservoir of integron-borne gene cassettes coding for diverse proteins including antibiotic-resistance. In: Biotechnology for people. ISBN:978-93-80663-86-9 (ed. S. Mukherjee), p. 50-59.Levant Books, Kolkata.
  5. Saha Bhowal S, Chakraborty R. 2013. Sulfur lithotrophy by acid-tolerant bacteria in acid-mine drainage. In: Biotechnology for people. ISBN:978-93-80663-86-9 (ed. S. Mukherjee), p. 77-86.Levant Books, Kolkata.
  6. Tiwary BK, Pradhan K, Nanda AK, Bothra AK, Chakraborty R. 2013. Basics of Computer-aided drug design. In: Biotechnology for people. ISBN:978-93-80663-86-9 (ed. S. Mukherjee), p. 151-167.Levant Books, Kolkata
  7. Yadav K K, Mandal A K, Chakraborty R. 2012. Biology of Bacterial biofilms. In: Biology of Plants and Microbes.ISBN: 978-93-80663-63-0 (eds. D. Bose and S. Roy), Levant Books, Kolkata 14.
  8. Chakraborty R, Roy P. 2006. Microbial genomics as an integrated tool for developing Biosensors for toxic trace elements in the environment. In Trace Elements in the Environment: Biogeochemistry, Biotechnology, and Bioremediation. P. 170-197 (editors: MNV Prasad et. Al.), CRC press, USA.
  9. Bhowal S, Bhadra B, Chakraborty R. 2005.Transposon mutagenesis of a metal resistant Gram negative isolate of river Torsa to target the genetic loci responsible for resistance to cobalt and nickel . In Stress Biology. Narosa Publishing House, New Delhi. ISBN-13: 978-8173196652 (eds. U. Chakraborty and B. Chakraborty).
  10. Bhadra B, Chakraborty R. 2005. Molecular screening of cobalt and nickel resistant gram negative isolates of river Torsa for the presence of homologous sequences of well characterized resistance genetic system . In Stress Biology. Narosa Publishing House, New Delhi. ISBN-13: 978-8173196652 (eds. U. Chakraborty and B. Chakraborty).
  11. Roy P, Sengupta A, Chakraborty R, Lahiri C, Ghosh W. 2002. Chemotaxis of Acidithiobacillus ferrooxidans vis-à-vis Mineral-microbe interaction. In Mineral Biotechnology. Allied Publishers Pvt. Ltd. New Delhi. ISBN 81-7764-349-5. (eds. L. B. Shukla and V. N. Misra).

    Edited International Journal Volume (Special Issue):
  12. Editors:MadhabK.Chattopadhyay,RanadhirChakraborty,Hans-Peter Grossart, Gundlapally S. Reddy, and Medicharla V. Jagannadhamuest. 2015. Antibiotic Resistance of Bacteria. Special issue published in “BioMed Research International”

    Journals:

  13. Roy C, Alam M, Mandal S, Haldar PK, Bhattacharya S, Mukherjee T, Roy R, Rameez MJ, Misra AK, Chakraborty R, Nanda AK, Mukhopadhyay SK, Ghosh W. 2016. Global Association between Thermophilicity and Vancomycin Susceptibility in Bacteria. Front Microbiol. 31;7:412. doi: 10.3389/fmicb.2016.00412. eCollection 2016.PMID: 27065976 Impact Factor: 4.0
  14. Pradhan K,    Tiwary BK,  Hossain M,  Chakraborty R and    Nanda AK. 2016. A mechanistic study of carbonyl activation under solvent-free conditions: evidence drawn from the synthesis of imidazoles. RSC Adv. 6, 10743-10749 DOI: 10.1039/C5RA16386B. Impact Factor: 3.84
  15. Mandal SM, Pati BR, Chakraborty R, Franco OL. 2016. New insights into the bioactivity of peptides from probiotics. Front Biosci (Elite Ed). 2016 Jun 1;8:450-9. PMID: 27100351. Impact Factor: 3.52
  16. Tiwary, B. , Kumar, A. , Pathak, R. , Pandey, N. , Yadav, K. and Chakraborty, R. 2016. The Locus PgaABCD of Acinetobacter junii Putatively Responsible for Poly-β-(1,6)-N-Acetylglucosamine Biosynthesis Might Be Related to Biofilm Formation: A Computational Analysis. Advances in Microbiology, 6, 222-232. doi: 10.4236/aim.2016.63022. Global Impact Factor: 0.765.
  17. Tiwary BK , Pradhan  K, Nanda  AK, Chakraborty R. 2015. Implication of  Quinazoline-4(3H)-ones in Medicinal Chemistry: A Brief Review. J Chem Biol Ther  1: 104. doi: 10.4172/jcbt.1000104
  18. Mandal SM, , Chakraborty A, Hossain M, Mahata D, Porto W F, Chakraborty R, Mukhopadhyay CK, Franco OL, Hazra, TK, BasaK A. 2015. Amphotericin B and Anidulafungin Directly Interact with DNA and Induce Oxidatve Damage inMammalian Genome. Molecular BioSystems 07/2015;  DOI:10.1039/C5MB00366K. Impact Factor: 3.18.
  19. Manna DK, Mandal AK, Sen IK, Maji P, Chakrabort S, Chakraborty R, Islam SS. 2015. Antbacterial and DNA degradaton potental of silver nanopartcles synthesized via green route. International Journal of Biological Macromolecules 07/2015; Impact Factor: 3.10
  20. Kumar A, Tiwary BK, Kachhap S, Nanda AK, Chakraborty R. 2015. An Escherichia coli Strain, PGB01, Isolated from Feral Pigeon Faeces, Thermally Fit to Survive in Pigeon,Shows High Level Resistance to Trimethoprim. PlosOne. DOI:10.1371/journal.pone.0119329. Impact Factor: 3.53 PMID-25750990
  21. Tiwary BK, Bihani S, Kumar A, Chakraborty R, Ghosh R. 2015. The in vitro cytotoxic actvity of ethno-pharmacological important plants of Darjeeling district of West Bengal against different human cancer cell lines. BMC Complement Altern Med. 7;15:22. Impact Factor: 2.02. PMID: 2588741.
  22. Chattopadhyay, M. K., Chakraborty, R., Grossart, H. P., Reddy, G. S., & Jagannadham, M. V. 2015. Antbiotc Resistance of Bacteria (Editorial). BioMed Research International, 2015. Artcle ID 501658. Impact Factor: 1.579
  23. Mandal, A. K., Sen, I. K., Maity, P., Chattopadhyay, S., Chakraborty, R., Roy, S., & Islam, S. S. 2015. Structural elucidaton and biological studies of a novel exopolysaccaride from Klebsiella pneumoniae PB12. International journal of biological macromolecules.79: 413-22. Impact Factor: 3.10. PMID-25999015
  24. Saha S, Nayak S, Bhattacharyya I, Saha S, Mandal AK, Chakraborty S, Bhattacharyya R, Chakraborty R, Mandal SM, Basak A. 2014. Understanding the Patterns of Antbiotc Susceptbility of Bacteria Causing Urinary Tract Infecton in West Bengal, India. Frontiers in Microbiology 5: 463; doi 10.3389/fmicb.2014.00463. Impact Factor : 4.0 PMID-25278932
  25. Ghosh R, Tiwary BK, Kumar A, Chakraborty R. 2014. Guava leaf extract inhibits quorum-sensing and Chromobacterium violaceum induced lysis of human hepatoma cells: whole transcriptome analysis reveals differental gene expression. PlosOne. DOI 10.1371/journal.pone.0107703. Impact Factor: 3.53 PMID-25229331 Page 26 of 10
  26. Tiwary BK, Kumar A, Nanda AK, Chakraborty R. 2014. A Study on Optmizaton of Marigold Petal Yield, Pure Lutein, and Formulaton of Free-Flowing Lutein Esters. Journal of Crop Science and Biotechnology (Springer). DOI No.10.1007/s12892- 014-0049-6. Impact Factor (yet to be decided).
  27. Chakraborty S, Mandal AK, Sarwar S, Singh P, Chakraborty R, Chakraborty P. 2014. Bactericidal Effect of Polyethyleneimine Capped ZnO Nanopartcles on Multple Antbiotc Resistant Bacteria Harboring Genes of High-Pathogenicity Island. Colloids and Surfaces B :Biointerfaces.http://dx.doi.org/10.1016/j.colsurfb.2014.03.044. Impact Factor: 4.29 PMID-24937133
  28. Tiwary BK, Pathak RK, Pradhan K, Nanda AK, Bothra AK, Chakraborty R. 2014. Evaluaton of drug candidature of some Quinazoline-4-(3H)-ones as inhibitor of human didydrofolate reductase enzyme: Molecular docking and Insilico studies. International Journal of Pharmacy & Pharmaceutical Sciences. 5. Supplement 2, 393-400. Impact Factor: 1.59
  29. Tiwary BK, Zirmire RK, Pradhan K, Nanda AK, Chakraborty R. 2014. Preparaton and spectroscopic characterizaton of inclusion complex of 2-phenyl-4H-Benzo[d] [1,3]Oxacin-4-One and β-Cyclodextrin. International Journal of Pharmacy & Pharmaceutical Sciences. 6. Supplement 2, 176-79. Impact Factor: 1.59
  30. Sen IK, Mandal AK, Chakraborty R, Behera B, Yadav KK, Mait TK, Islam SS. 2013. Structural and immunological studies of an exopolysaccharide from Acinetobacter junii BB1A. Carbohydate Polymer. 101: 188-195 Impact Factor: 3.48 PMID-24299764
  31. Sen IK, Mandal AK, Chakraborty S, Dey B, Chakraborty R, Islam SS. 2013. Green synthesis of silver nanopartcles using glucan from mushroom and study of antibacterial actvity. Int. J. Biol. Macromolecules. 62: 439 – 449. Impact Factor: 3.10 PMID-24076192
  32. Kumar A, Ince İ, Katı A, Chakraborty R. 2013. Brevibacterium siliguriense sp. nov., a facultatvely oligotrophic bacterium isolated from river water. Int. J. Sys.Evol. Microbiol. 63: 511-515. Impact Factor: 2.80 PMID-22523163
  33. Mukherjee S, Kumar D, Nanda AK, Chakraborty R. 2013. 16S rRNA gene sequence analyses of the metagenome derived from waters of river Mahananda at Siliguri: An approach to understand bacterial diversity. Ind. J. Biotechnol. 12: 80-87. Impact Factor : 0.6
  34. Chakraborty R, Kumar A, Bhowal SS, Mandal AK, Tiwary BK, Mukherjee S. 2013.Diverse gene cassettes in class 1 integrons of facultatve oligotrophic bacteria of river Mahananda, West Bengal, India. PLoS One. 8(8):e71753. doi: 10.1371/journal.pone.0071753. Impact Factor: 3.53 PMID-23951238
  35. Yadav KK, Mandal AK, Chakraborty R. 2013. Copper susceptbility in Acinetobacter junii BB1A is related to the producton of extracellular polymeric substances.Page 27 of 10Antonie Van Leeuwenhoek. 104(2):261-9. doi: 10.1007/s10482-013-9946-9. Epub2013 Jun 12. Impact Factor: 2.07 PMID-23756604
  36. Ghosh W, Alam M, Roy C, Pyne P, George A, Chakraborty R, Majumder S, Agarwal A, Chakraborty S, Majumdar S, Gupta SK. 2013. Genome implosion elicits hostconfinement in Alcaligenaceae: evidence from the comparatve genomics of Tetrathiobacter kashmirensis, a pathogen in the making. PLoS One. 8(5):e64856. doi: 10.1371/journal.pone.0064856. Print 2013. Impact Factor: 3.53 PMID-23741407
  37. Mandal AK, Yadav KK, Sen IK, Kumar A, Chakrabort S, Islam SS, Chakraborty R. 2013. Partal characterizaton and flocculatng behavior of an exopolysaccharide produced in nutrient-poor medium by a facultatve oligotroph Klebsiella sp. PB12. J Biosci Bioeng. 115(1):76-81. doi: 10.1016/j.jbiosc.2012.08.006. Epub 2012 Sep 1. Impact Factor: 1.74 PMID- 22944200
  38. Yadav K K, Chakraborty R. 2012. Designing primers to fish auto-inducer synthase gene(s) of the quorum sensing system in γ -proteobacteria and their in-silico PCR validation. NBU J. Plant Sciences Vol. 6, No.1March 2012 p.25-29
  39. Yadav KK, Mandal AK, Sen IK, Chakrabort S, Islam SS, Chakraborty R. 2012. Flocculating property of extracellular polymeric substances produced by a biofilm forming bacterium Acinetobacter junii BB1A. Appl Biochem Biotechnol. 168(6):1621-34. doi: 10.1007/s12010-012-9883-5. Epub 2012 Sep 12. Impact Factor: 1.94 PMID- 22968590.
  40. Kumar A, Chakrabort S, Joshi P, Chakrabart P, Chakraborty R. A multple antibiotic and serum resistant oligotrophic strain, Klebsiella pneumoniae MB45 having novel dfrA30, is sensitve to ZnO QDs. Ann Clin Microbiol Antimicrob. 10:19. doi: 10.1186/1476-0711-10-19. Impact Factor: 2.19. PMID-21595893
  41. Bhowal S, Chakraborty R. 2011. Five novel acid-tolerant oligotrophic thiosulfate metabolizing chemolithotrophic acid mine drainage strains affiliated with the genus Burkholderia of Betaproteobacteria and identficaton of two novel soxB gene homologues. Res. Microbiol. 162: 436-45. Impact Factor: 2.83 PMID-21349327
  42. Bhadra B, Nanda A K, Chakraborty R. 2011. Enterobacter nickelidurans sp. nov., a novel nickel tolerant enterobacteria isolated from Torsa river water of India. NBU J Plant Sc. 5:15-23
  43. Kumar A, S. Mukherjee, Chakraborty, R. 2010. Characterizaton of a novel Trimethoprim Resistance gene, dfr28, in Class 1 integron of an Oligotrophic
    Acinetobacter johnsonii Strain, MB52, isolated from River Mahananda, India. Microbial Drug Resistance.16: 29-37. Impact Factor : 2.52 PMID- 20192821
  44. Gurung A, Chakraborty R. 2009. Acidithiobacillus ferrooxidans in alleviatng the inhibitory effect of thiosulfate on the growth of acidophilic Acidiphilium species isolated from Garubathan AMD samples, India. Can J. Microbiol. 55: 1040-1048. Impact Factor: 1.221 PMID-19898546
  45. Sarkar S, Chakraborty R. 2008. Quorum sensing in metal tolerance of Acinetobacter junii BB1A is associated with biofilm producton. FEMS Microbiol Lett. 282: 160-165. Impact Factor: 2.72 PMID-18397291 Page 28 of 10
  46. Sarkar C, Mitra PK, Saha S, Nayak CR, Chakraborty R. 2008. Effect of copper hydroquinone complex on oxidatve stress-related parameters in human
    erythrocytes (in Vitro). Toxicol. Mech. & Methods. 19. DOI: 10.1080/15376510802164683. Impact Factor: 1.37. PMID-19778251
  47. Dey D, Mukhopadhyay A, Chakraborty R. 2008. A novel bacterial pathogen (Enterobacter sp.) isolated from the leaf roller, Caloptlia theivora of tea of Darjeeling foothills. W. J. Microbiol. & Biotechnol. 24: 2727-2729. Impact Factor: 1.779.
  48. Mukherjee S, Chakraborty R. 2007. Conjugaton potental and class 1 integron carriage of resident plasmids in river water copiotrophs. Acta Microbiol Immunol Hung. 254:379-397. Impact Factor: 0.778. PMID 18088011.
  49. Nanda AK, Ganguli S, Chakraborty R. 2007. Antbacterial actvity of some 3-(arylideneamino)-2-phenylquinazoline-4(3H)-ones: synthesis and preliminary QSAR studies. Molecules.12:2413-2426. Impact Factor: 2.79. PMID 17978766.
  50. Bhadra B, Nanda AK, Chakraborty R. 2007. Fluctuaton in recoverable nickel and zinc resistant copiotrophic bacteria explained by the varying zinc ion content of Torsa River in different months. Arch Microbiol.188:215-224. Impact Factor: 1.86. PMID 17464499.
  51. Mukherjee S, Chakraborty R. 2006. Incidence of class 1 integrons in multiple antbiotc-resistant Gram-negative copiotrophic bacteria from the River Torsa in India. Res Microbiol.157:220-226. Impact Factor: 2.83. PMID 16239097.
  52. Bhadra B, Nanda AK, Chakraborty R. 2006. Inducible nickel resistance in a river water isolate of India phylogenetcally ascertained as a novel strain of Acinetobacter junii. W. J. Microbiol. & Biotechnol. 22: 225-232. Impact Factor: 1.779.
  53. Bhadra B, Roy P, Chakraborty R. 2005. Serratia ureilytica sp. nov., a novel urea utilizing species. Int J Syst Evol Microbiol. 55:2155-2158. Impact Factor: 2.80 PMID 16166724.
  54. Bhadra B., Chakraborty, R., Das, S., Nanda, A.K. 2005. Investgaton of some basic water quality parameters of the north Bengal Terai river Kaljani-a tributary of river Torsa, and comparison thereof with the mainstream. J. Environ. Biol. 26: 277-86. Impact Factor: 0.68. PMID 16161986.
  55. Mukherjee, S., Bhadra, B., Chakraborty, R., Gurung, A., Some, S., Chakraborty, R. 2005. Unregulated use of antbiotcs in Siliguri city vis-a-vis occurrence of MAR bacteria in community waste water and river Mahananda and their potental for resistance gene transfer. . J. Environ. Biol. 26: 229-38. Impact Factor: 0.68. PMID 16161978.
  56. Deb, C., Chakraborty, R., Ghosh, AN., Mandal NC., Mukherjee, T., Roy, P. 2003. A generalized transducing thiophage (TPC‐1) of a facultatve sulfur chemolithotrophic bacterium, Bosea thiooxidans CT5, of α‐Proteobacteria, isolated from Indian soil. FEMS Microbiology letters. 227: 87-92. Impact Factor: 2.72 PMID-14568152 Page 29 of 10
  57. Bhadra, B., Mukherjee, S., Chakraborty, R., Nanda, AK. 2003. Physico-chemical and bacteriological investgaton on the River Torsa of North Bengal. J. Environ. Biol. 24: 125-33. Impact Factor: 0.68 . PMID-12974452
  58. Chakraborty, R., Singh, A., Lahiri, C., Deb, C., Roy, P. 2002. Colony morphology mutants of chemolithotrophic Acidithiobacillus ferrooxidans are associated with altered genomic distributon of family 1 repettveDNA sequence. Current Science. 82: 1009-1014. Impact Factor: 0.926.
  59. Chakraborty, R., Deb, C., Lohia, A., Roy, P. 1997. Cloning and Characterizaton of a High-Copy-Number Novel Inserton Sequence from Chemolithotrophic Thiobacillus ferrooxidans. Plasmid. 38: 129-134. Impact Factor: 1.61.
  60. Chakraborty, R., Roy, P. 1992. Chemotaxis of chemolithotrophic Thiobacillus ferrooxidans toward thiosulfate. FEMS Microbiology letters 98: 9-12. Impact Factor:2.72
  61. Sarkar, P.K., Chakraborty, R. 1991. Enrichment and isolaton of caffeine degrading bacteria (Pseudomonas spp) from brewed tea waste dumping ground. Ind. J. Expl. Biol. 29: 679-80. Impact Factor : 0.835